Study Overview

  • Study directors:Elysa Marco, MD and Kevin Shapiro, MD 

  • Recruiting: Yes 

  • Study title: Ecopipam Tablets to Study Tourette’s Disorder in Children, Adolescents and Adults 

  • Conditions: Tourette’s Syndrome/Tourette’s Disorder and tics 

  • Purpose: The purpose of this study is to find out whether ecopipam, a selective dopamine blocker, reduces tics in individuals with Tourette’s Syndrome. 


Inclusion criteria

  • Above 6 years old 

  • Diagnosed (or suspected) Tourette’s Syndrome 

  • Moderate-to-severe tics 

Exclusion criteria

  • History of seizures 

  • Unable to swallow tablets 

  • Unstable medical or psychiatric illness 

  • Currently using certain medications to reduce tics – contact our study team to discuss

Emalex website graphic

What is Involved? 

  • Testing: Comprehensive tic assessments, psychiatric questionnaires, and medical evaluations 

  • Frequency of visits:  Once a month for three months, followed by weekly/biweekly assessments for an additional three months if medication is effective in reducing tics 

  • Costs:No costs will be charged for any of the study procedures. We are also able to support with Lyfts or reimburse for mileage to and from visits

  • Payment: In return for the time, effort, and travel expenses, adults will be compensated $100 per visit and children with their caregivers will be compensated $175 per visit 

Location and Contact Information 

Marin and Glendale State Pins