Study for Adolescents with Tourette’s Syndrome

Study directors: Kevin Shapiro, MD PhD, and Elysa Marco, MD

Recruiting: Yes

Study Title: A double-blind, placebo-controlled, phase IIb, multi-center, 12-week prospective study to evaluate the efficacy and safety of gemlapodect in adult and adolescent patients with Tourette’s Syndrome

Condition: Tourette’s Syndrome

Purpose: The purpose of this study is to find out whether gemlapodect, an investigational medication, can reduce tics in individuals with Tourette’s Syndrome.

Eligibility

Inclusion criteria:

  • 16-17 years old

  • Diagnosed (or suspected) Tourette’s Syndrome

  • Moderate-to-severe motor and vocal tics

Exclusion criteria:

  • Uncontrolled seizure disorders

  • Unstable medical or psychiatric illness

  • Conditions such as functional tic-like disorder, Huntington’s chorea, malignant TS, autism, severe anxiety, bipolar disorder, schizophrenia, or Parkinson’s disease

  • Current CBT, CBiT, or neurostimulation

  • Current use of medications for tics – contact our study team to discuss

What is Involved?

  • Testing: Comprehensive tic assessments, psychiatric questionnaires, and medical evaluations

  • Frequency of visits: 12 visits over 4 months, 10 in-clinic and 2 telehealth visits

  • Costs: No costs will be charged for any of the study procedures

  • Payment: In return for the time, effort, and travel expenses, participants will be compensated $100 per visit

Location and Contact Information